Sylvester Comprehensive Cancer Center

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Michael D. Norenberg, M.D.

General Information

Michael D. Norenberg, M.D.

Languages

  • English
  • Spanish
  • German

Certifications

  • American Board of Pathology-Neuropathology
  • American Board of Pathology-Anatomic

Specialties

  • Pathology-Neuropathology
  • Pathology-Anatomic

Roles

  • Director, Neuropathology and Neuropathology Research
  • Member of the Neuroscience Program, and The Miami Project to Cure Paralysis (Affiliate Faculty)
  • Professor, Department of Pathology, Biochemistry & Molecular Biology, Neurology, Neurosurgery

Clinical Interests

Metabolic encephalopathies, neurotrauma, and neurodegenerative disorders.

Research Interests

Normal function and properties of glia; neurotransmitter transport in glia; role of glia and steroids in neuroprotection; mechanisms and significance of reactive gliosis; role of glia in various neurological conditions (trauma, aging/Alzheimer's disease, Parkinson's disease, brain edema, liver failure); the role of oxidative stress and the mitochondrial permeability transition in CNS trauma and liver failure. Additionally, we are investigating the cellular and molecular events associated with human spinal cord injury. Our studies utilize animal models of human disease and the use of cell culture (astrocytes, microglia, neurons, endothelial cells). Techniques employed in our laboratory include morphology (including immunohistochemistry, confocal microscopy, in situ hybridization, electron microscopy), molecular biology, analysis of membrane receptors, calcium imaging and various biochemical / pharmacological methods.

Awards

Distinguished Teacher, White House Commission
Career Development Awards, Veterans
Merck Chemistry Prize, Trinity College

Education

1972 Postdoctoral Fellow
Strong Memorial Hospital
1970 Associate Resident
Strong Memorial Hospital
1969 Assistant Resident
Rochester General Hospital
1966 Internship
Strong Memorial Hospital
1965 M.D.
University of Rochester School of Medicine and Dentistry
1960 B.S.
Trinity College

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