Sylvester Comprehensive Cancer Center

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Allan D. Levi, M.D., Ph.D., FACS

General Information

Allan D. Levi, M.D., Ph.D., FACS

Contact

  • Fax: 305-243-3247

Languages

  • English
  • French
  • Italian
  • Spanish

Certifications

  • American Board of Neurological Surgery

Video Introduction

CV

Specialties

  • Neurological Surgery

Roles

  • Chairman of Neurosurgery, University of Miami MILLER School of Medicine Service
  • Chief of Neurosurgery, Jackson Memorial Hospital
  • Professor, Departments of Neurological Surgery, Orthopedics, and Rehabilitation Medicine

Clinical Interests

Cellular Transplantation, Spinal Cord Injury, Peripheral Nerve Injury, Hypothermia, Stem Cells My research interests have focused on developing cellular transplantation strategies to repair injuries within both the human central and peripheral nervous system. Schwann cells are the principal support cells with the peripheral nervous system and have the capacity to promote regeneration of central nervous system neurons as well as remyelinate central axons which have lost their insulation. I have focused much of my previous research efforts in furthering our understanding of the biology of human Schwann cells which have been isolated using cell culture techniques. The results of these studies have demonstrated that human Schwann cells have the capacity to form myelin after transplantation within immune deficient rodent models and that their numbers can be significantly increased with addition of growth factors. My current research interests involve serving as (1) PI on intravascular hypothermia after human cervical spinal cord injury (2) co-PI on the FDA approved trial of “The Safety of Autologous Human Schwann Cells in Subjects with Sub-acute Spinal Cord Injury (SCI)” and (3) PI on the clinical development and characterization of the use of autologous human Scwhann cells for peripheral nerve injuries with a lengthy gap to promote peripheral nerve regeneration (4) Site PI of a Phase II Proof-of-Concept Study of the Safety and Efficacy of HuCNS-Stem Cell Transplantation in Cervical Spinal Cord Injury

Research Interests

Cellular Transplantation, Spinal Cord Injury, Peripheral Nerve Injury, Hypothermia, Stem Cells My research interests have focused on developing cellular transplantation strategies to repair injuries within both the human central and peripheral nervous system. Schwann cells are the principal support cells with the peripheral nervous system and have the capacity to promote regeneration of central nervous system neurons as well as remyelinate central axons which have lost their insulation. I have focused much of my previous research efforts in furthering our understanding of the biology of human Schwann cells which have been isolated using cell culture techniques. The results of these studies have demonstrated that human Schwann cells have the capacity to form myelin after transplantation within immune deficient rodent models and that their numbers can be significantly increased with addition of growth factors. My current research interests involve serving as (1) PI on intravascular hypothermia after human cervical spinal cord injury (2) co-PI on the FDA approved trial of “The Safety of Autologous Human Schwann Cells in Subjects with Sub-acute Spinal Cord Injury (SCI)” and (3) PI on the clinical development and characterization of the use of autologous human Scwhann cells for peripheral nerve injuries with a lengthy gap to promote peripheral nerve regeneration (4) Site PI of a Phase II Proof-of-Concept Study of the Safety and Efficacy of HuCNS-Stem Cell Transplantation in Cervical Spinal Cord Injury

Awards

Top Doctors (Castle Connolly)
Elected Member of the American Academy of Neurological Surgery
Best Doctors
Elected Member of the Senior Neurosurgical Society
Roberto C. Heros - Best Resident Teacher Award in Neurosurgery

Education

1995 Spine Fellowship
Barrow Neurological Institute
1994 Ph.D.
University of Miami
1987 Residency
University of Toronto
1986 MD
University of Ottawa

Publications

Biography

Allan Levi MD, PhD, FRCS(C), FACS, specializes in the field of spine and peripheral nerve surgery.  His neurosurgical training was completed at the University of Toronto.  He did specialized fellowship training in spine surgery at the Barrow Neurological Institute in Phoenix, Arizona. He completed this Ph.D. under the supervision of Dr. Richard Bunge between ‘91 – '94. Dr. Levi joined the faculty at the University of Miami in 1997.

Dr. Levi serves as Chief of the Neurospine service and Spine Fellowship Director at Jackson Memorial Hospital. He also serves as the Chief of Neurosurgery at University of Miami Hospital. He has a busy clinical practice which includes the treatment of numerous spinal disorders including but not limited to degenerative spine diseases, spinal trauma, rheumatoid arthritis, tumors, Chiari malformations, syrinxes, etc. The latest technology is available within the operating rooms including complex spinal instrumentation, artificial cervical discs, spinal cord monitoring and minimally invasive spine surgery.

Dr. Levi also has a special interest in peripheral nerve disorders and treats patients with nerve entrapments, tumors and trauma.

Dr. Levi has over 100 peer-reviewed publications and over 25 text book chapters. He serves as a reviewer for several journals in neurosurgery and neuroscience. He over-sees a number of on-going clinical trials in the field of spinal cord injury including cellular transplantation of Schwann cells and stem cells and the use of hypothermia for acute spinal cord injury.

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