Sylvester Comprehensive Cancer Center

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Glen Manzano, M.D.

General Information

Glen  Manzano, M.D.


  • Fax: 305-243-3247


  • English
  • Spanish


  • American Board of Neurological Surgery

Video Introduction



  • Neurological Surgery


  • Assistant Professor of Clinical Neurosurgery
  • Co-Director, Jackson Memorial Hospital Acute Spinal Cord Injury Unit
  • Director, University of Miami Spine Tumor Initiative

Clinical Interests

Minimally invasive spine surgery, spinal cord tumors, total disc replacement, spinal reconstruction, syringomyelia, spinal cord injury, and surgery for neuropathic pain. 

Research Interests

Spinal Cord Tumors
Metastatic Tumors of the Spine
Minimally Invasive Spine Surgery
Image Guided Spine Surgery
Spinal Instrumentation
Degenerative Spinal Disorders
Compression Fractures
Spinal Inflammatory/ Infectious Disorders
Chiari Malformation
Spinal Cord Injury
Spinal Cord Injury Pain


Hubert L. Rosomoff Research Award
Outstanding Surgical Intern of the Year


2009 Residency Neurological Surgery
U. of Miami Department of Neurosurgery/Jackson Memorial Hospital
2007 Fellowship Complex Spine Surgery
U. of Miami Department of Neurosurgery/Jackson Memorial Hospital
2006 Resident Research Year
University of Miami Department of Neurosurgery
2003 Surgical Internship
University of Miami Department of Surgery
2002 MD
University of Miami School of Medicine
1995 BS
University of Notre Dame


  • Hernandez-Duran S, Hanft S, Komotar RJ, Manzano GR. The role of stereotactic radiosurgery in the treatment of intramedullary spinal cord neoplasms: a systematic literature review. Neurosurg Rev. 2016 Apr;39(2):175-83.
  • Hernández-Durán S, Bregy A, Shah AH, Hanft S, Komotar RJ, Manzano GR. Primary spinal cord glioblastoma multiforme treated with temozolamide. J Clin Neurosci. 2015 Dec;22(12):1877-82.
  • Manzano GR, Casella G, Wang MY, Vanni SV, Levi AD. A prospective randomized trial comparing expansile cervical laminoplasty versus cervical laminectomy and fusion for multilevel cervical myelopathy. Neurosurgery. 2012 Feb;70(2):264-77.
  • Manzano G, Green BA, Vanni S, Levi AD. Contemporary management of adult intramedullary spinal tumors - pathology and neurological outcomes related to surgical resection. Spinal Cord. 2008 Aug;46(8):540-6.
  • Sheth RN, Manzano G, Li X, Levi AD. Transplantation of human bone marrow-derived stromal cells into the contused spinal cord of nude rats. J Neurosurg Spine. 2008 Feb;8(2):153-162.
  • Elhammady M, Manzano GR, Lebwohl N, Levi AD: Leiomyosarcoma metastases to the spine. Case series and review of the literature. J of Neurosurgery – Spine 178-183, 2007.
  • Lee TT, Singh RV, Manzano GR, Green BA. Contemporary Management of Spinal Cord Injury. In: Neurosurgery Quarterly, DL Long, ed., Springer Verlag, Philadelphia, PA, Vol 9(2), pp. 138-153, 1999.
  • Lee TT, Manzano GR, Green BA. Modified open-door cervical expansile laminoplasty for spondylitic myelopathy: Technical notes, clinical and radiographic outcome and predictors for gait improvement. J Neurosurg 86(1):64-68, 1997.


Dr. Manzano completed his undergraduate education at the University of Notre Dame and earned his medical degree from the University of Miami School of Medicine. He went on to complete his neurosurgery residency and complex spine fellowship at the University of Miami/Jackson Memorial Medical Center. Dr. Manzano has resided in south Florida for over 30 years, and is fluent in Spanish.

Dr. Manzano is subspecialized in the field of complex spine and spinal cord surgery. His clinical expertise includes the treatment of degenerative spine disease, spine trauma, spine and spinal cord tumors, spinal inflammatory/infectious disease and osteoporotic compression fractures. He works with a multidisciplinary team of specialists who can offer comprehensive care for the spine patient. His philosophy includes maximizing conservative therapy as well thoroughly educating and communicating with those patients who require surgery in order to optimize their potential for success. He employs minimally invasive techniques, whenever applicable, to treat the complete spectrum of spine pathology.


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