Breelyn A. Wilky, M.D.
- American Board of Internal Medicine
- American Board of Internal Med-Medical Oncology
- Hematology/Oncology - Internal Medicine
- Internal Medicine
- Assistant Professor of Medical Oncology
- Member, Molecular Oncology and Experimental Therapeutics (MOET) Program
Alpha Omega Alpha
Conquer Cancer Foundation/ASCO Young Investigator Award
Alpha Omega Alpha Postgraduate Award
Connie Caplan Medical Oncology Fellowship
Gold Humanism Honor Society
Johns Hopkins University
2006-2009 Internship and Residency
Johns Hopkins Hospital
2006 M.D. with Distinction in Research
University of Medicine and Dentistry of New Jersey – Robert Wood Johnson Medical School
- Kikuchi K, Hettmer S, Imran Aslam M, Michalek J, Laub W, Wilky B, Loeb D, Rubin B, Wagers A, Keller C. Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma. PLOS Genetics, 2014. 10(1):e1004107.
- Trucco MM, Awad O, Wilky BA, Goldstein SD, Huang R, Walker RL, Shah P, Katuri V, Gul N, Zhu YJ, McCarthy EF, Paz-Priel I, Meltzer PS, Austin CP, Xia M, Loeb DM. A Novel Chordoma Xenograft Allows In Vivo Drug Testing and Reveals the Importance of NF-?B Signaling in Chordoma Biology. PLOS One, 2013. 8(11): e79950.
- Wilky BA, Montgomery E, Guzzetta A, Ahuja N, Meyer C. Extrathoracic location and â€śborderlineâ€ť histology are associated with recurrence of solitary fibrous tumors after surgical resection. Ann Surg Oncol 2013, 20(13) 4080-9.
- Wilky BA, Meyer CF, Trent JC. Pazopanib in sarcomas: Expanding the PALETTE. Curr Opin Oncol. 2013, 25(4):373-8.
- Scannell C, Pederson E, Mosher J, Krook M, Nicholls L, Wilky BA, Loeb D, Lawlor E. LGR5 is expressed by Ewing sarcoma and potentiates Wnt/Ăź-catenin signaling. Front Oncol. 2013, 3:81.
- Thornton KA, Chen AR, Trucco MM, Shah P, Wilky BA, Gul N, Carrera-Haro MA, Ferreira MF, Shafique U, Powell JD, Meyer CF, Loeb DM. A dose finding study of temsirolimus and liposomal doxorubicin for patients with recurrent and refractory bone and soft tissue sarcoma. Int J Cancer 2013, 133(4): 997-1005.
- Wilky BA, Loeb DM. Beyond Palliation: Therapeutic Applications of 153Samarium-EDTMP. Clin Exp Pharmacol. 2013, 3:131.
My clinic consists of patients with sarcomas and other bone/soft tissue tumors, including gastrointestinal stromal tumors (GIST), desmoid fibromatosis, pigmented villonodular sclerosis (PVNS), chordomas, and solitary fibrous tumors. I am also a clinical/translational researcher, with a focus on bringing new targeted therapies into early phase clinical trials for sarcoma patients.