Sylvester Comprehensive Cancer Center

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Ofelia A. Alvarez, M.D.

General Information

Ofelia A. Alvarez, M.D.


  • English
  • Spanish


  • American Board of Pediatrics
  • American Board of Pediatrics-Pediatric Hematology-Oncology


  • Pediatrics
  • Pediatric Hematology-Oncology (Pediatrics)


  • Medical Director, Pediatric Sickle Cell Program
  • Professor of Clinical Pediatrics

Clinical Interests

Sickle cell disease, pediatric hematology-oncology


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University of Puerto Rico
University of Puerto Rico
Childrens Hospital Los Angeles


  • Adamkiewcz TV, Abboud MR, Paley C, Olivieri N, Kirby-Allen M, Vichinsky E, Casella JF, Alvarez OA, Barredo JC, Lee MT, Iyer RV, Kutlar A, McKie KM, McKie V, Odo N, Gee B, Kwiatkowski JL, Woods GM, Coates T, Wang W, Adams RJ. Serum Ferritin Response to Iron Load from Blood Transfusion in Children with Sickle Cell Disease is Non-Linear, High Levels Are Associated with Significant Iron Overload and Liver Injury. Blood 2009 Aug 31. [Epub ahead of print]
  • Ware RE, Rees RC, Sarnaik SA, Iyer RV, Alvarez OA, Casella JF, Shulkin BL, Shalaby-Rana E, Strife F, Miller JH, Lane PA, Wang WC, Miller ST, and the BABY HUG Investigators. Renal Function in Infants with Sickle Cell Anemia: Baseline Data from the BABY HUG Trial. J Pediatr. 2009 Oct 30. [Epub ahead of print]
  • Alvarez O, Rodriguez-Cortes H, Robinson N, Lewis N, Diaz Pow-Sang C, Lopez-Mitnik G, Paley C. Adherence to Deferasirox in Children and Adolescents with Sickle Cell Disease during One Year of Therapy. J Pediatr Hematol Oncol 2009 Sep
  • Aygun B, McMurray MA, Schultz WH, Kwiatkowski JL, Hilliard L, Alvarez O, Heeney M, Kalinyak K, Lee MT, Miller S, Helms RW, Ware RE for the SWiTCH Trial Investigators. Short Report: Chronic Transfusion Practice for Children with Sickle Cell Anaemia and Stroke, British Journal of Hematology, 145 (4): 524-528, 2009.
  • Alvarez O, Lopez-Mitnik G, Zilleruelo G. Short-Term Follow-Up of Patients with Sickle Cell Disease and Albuminuria. Pediatr Blood & Cancer; 50: 1236-9, 2008.
  • Alvarez O, Montane B, Lopez G, Wilkinson J, Miller T. Early Blood Transfusions Protect Against Microalbuminuria in Children with Sickle Cell Disease. Pediatr Blood & Cancer, 47: 71-76, 2006.
  • Alvarez O, Zilleruelo G, Wright D, Montane B, Lopez-Mitnik G. Serum Cystatin C Levels in Sickle Cell Disease. Pediatric Nephrology, 21: 533-537, 2006.
  • The Optimizing Primary Stroke Prevention in Sickle Cell Anemia (STOP 2) Trial Investigators, Discontinuing Prophylactic Transfusions Used to Prevent Stroke in Sickle Cell Disease. New Engl J Med; 353: 2769-2778, 2005.

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