Sylvester Comprehensive Cancer Center

News

Courtesy: NCI Center for Cancer Research

Researchers Make Key Discovery Toward Stopping Colorectal Cancer

06.27.2017

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and other institutions have shown that a molecule developed by Stemsynergy Therapeutics (SSTC3) controls the progression of colorectal cancer in several cell lines and human tumor xenografts. SSTC3 modulates the WNT pathway but does not show the on-target toxicity normally associated with WNT inhibitors.

Her recovery has allowed Donna Robinson to travel and celebrate her good health.

A Cancer Survivor’s Story: ‘Incurable’ Meets Its Match

06.21.2017

In 2014, Donna Robinson had a routine colonoscopy. During the procedure, the physician detected a small mass. Two days later, on her 58th birthday, she received the bad news. The small mass was actually part of a very large mass that had grown through the wall of her intestine and into other locations in her abdomen. It was locally advanced pancreatic cancer, she was told — inoperable and incurable.

Marcela Vieira leads an active life of work and family, and still finds time to walk her dog for exercise.

A Cancer Survivor's Story: An ‘Angel’ Gave Her Life Back

06.15.2017

Marcela Vieira couldn’t believe that cancer kept coming back. Her first bout was with breast cancer in 2002, when she was only 36. It returned in 2010. In 2013, she was diagnosed with ovarian cancer. It also returned, in 2014. “At first you don’t believe it, and you ask, ‘Why me?’” she said.

Donald Kumin taking a practice swing in his yard.

A Cancer Survivor’s Story: Men Get Breast Cancer, Too

06.12.2017

Donald Kumin doesn’t look like someone who has cancer. The vibrant 88-year-old Delray Beach resident regularly plays golf with friends. He and his wife, Irene, are taking a cruise this fall, and at an age when many of their contemporaries have gone into assisted living, they are proud to be leading an active life from their own home.

From left, Carl H. June, M.D., Pasquale Benedetto, M.D., Mark L. Gonzalgo, M.D., Ph.D., Nipun Merchant, M.D., Alberto J. Caban-Martinez, D.O., Ph.D., M.P.H., Breelyn A. Wilky, M.D., and Stephen D. Nimer, M.D.

Zubrod Memorial Lecture Program Spotlights Faculty and Young Investigators

06.08.2017

Six physician-scientists were recognized for their contributions to cancer research and treatment as part of the Sylvester Comprehensive Cancer Center’s 18th Annual Zubrod Memorial Lecture and Sylvester Cancer Research Poster Session on May 19. Sylvester Director Stephen D. Nimer, M.D., hosted the event.

Leukemia cells.

Discovering AML’s Epigenetic Identity

06.07.2017

Maria Figueroa, M.D., a researcher at Sylvester Comprehensive Cancer Center and associate professor of human genetics at the University of Miami Miller School of Medicine, published a paper in the journal Cancer Discovery that provides new insights into how certain molecular pathways influence acute myeloid leukemia (AML).

Sylvia Daunert, Ph.D., Pharm.D., M.S., professor and Lucille P. Markey Chair of the Department of Biochemistry and Molecular Biology, and Omaida C. Velazquez, M.D., FACS, chair of surgery, at surgery research day.

Surgery Research Day Showcases Scientific Achievements

06.07.2017

Sylvester Comprehensive Cancer Center and the DeWitt Daughtry Family Department of Surgery at the University of Miami Miller School of Medicine hosted the inaugural surgery research day and Lily Altschuler Memorial Symposium in Pancreatic Cancer Research on May 12, showcasing scientific achievements of faculty and trainees.

Signing of the memorandum of understanding. From left, Gilberto Lopes, M.D., Thinh H. Tran, M.D., MBA, Barbara Ronda, MHSA, Jose Ramirez, M.D. and Brian M. Slomovitz, M.D.

Sylvester to Collaborate on Oncology Training in the Dominican Republic

06.07.2017

Sylvester Comprehensive Cancer Center and the University of Miami Miller School of Medicine recently signed a memorandum of understanding with the Dominican Republic’s Instituto de Oncologia Dr. Heriberto Pieter. The agreement allows Miller School oncology experts to provide their evidence-based expertise to improve cancer care, research and clinical trial initiatives and health outcomes in the Dominican Republic.

Joyce M. Slingerland, M.D., Ph.D.

Stopping VEGF, a Cancer Super-Villain

05.30.2017

For years, a protein called vascular endothelial growth factor (VEGF) has been known for its ability to generate new blood vessels. As tumors grow, and need more oxygen and nutrients, they secrete VEGF to increase their blood supply. That was a radical discovery 20 years ago, and some believed it would create many therapeutic opportunities against cancer.

Stephen D. Nimer, M.D.

Using Epigenetics to Fight Blood Cancers

05.30.2017

Researchers are trying to figure out why changes in the interactions of proteins can cause cancer. Stephen D. Nimer, M.D., director of Sylvester Comprehensive Cancer Center, was co-senior author on a paper, published in the journal PNAS, that describes how the protein DPF2 regulates blood production. High levels of DPF2 are seen in patients with acute myelogenous leukemia (AML).