Sylvester Comprehensive Cancer Center

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Noula Shembade, Ph.D., and Edward Harhaj, Ph.D.

Sylvester Researchers Discover Regulating Mechanism of Key Transcription Factor

02.25.2010

In many cancers, scientists have discovered that key gene regulators which normally control cell growth have either been turned off or mutated. That change in the regular pattern then allows unrestricted cell production and the creation of tumors. Sylvester researchers have discovered exactly how one critical regulator affects a transcription factor that is consistently turned on in most cancers.