A Miller School research study has found a potential new approach to halting the growth of acute myelogenous leukemia (AML), a deadly blood-borne cancer in adults and children. “We found that blocking an enzyme called PRMT4 caused leukemia cells to die,” said Stephen D. Nimer, M.D., Director of the Sylvester Comprehensive Cancer Center.
In a study led by Ramiro E. Verdun, Ph.D., assistant professor of medicine in the Division of Gerontology and Geriatric Medicine, researchers have uncovered a mechanism to repair different types of DNA double-strand breaks, highly toxic lesions that, if left unrepaired, can produce a permanent arrest of cell division or cell death. These findings open the door to establishing new tumor-targeted treatment strategies.
With the Interventional Radiology Section team lining the halls, a grateful patient and the Dean of the Miller School smiling broadly, Govindarajan Narayanan, M.D., associate professor of radiology, declared a “new day for Sylvester” as he unveiled the new angio suite at University of Miami Hospital and Clinics.
Each cyclist rode for a different reason -- one to remember a brother who succumbed to prostate cancer, another for a spouse who’s been fighting breast cancer for years. But all of the 2,500-plus riders who participated in this year’s Dolphins Cycling Challenge (DCC), shared a common goal: raising funds for the lifesaving treatments and research programs at Sylvester Comprehensive Cancer Center.
Seven Miller School investigators are among the 31 recipients of the 2013 research grants the Florida Department of Health awarded recently to help researchers at state university and research institutes find cures for cancers and tobacco-related diseases.
Celia Schieffelin was one of more than 100 students and employees who donned workout clothes and sneakers last Wednesday to pedal, pant, and perspire at the Dolphins Cycling Challenge Spin-a-Thon, which is geared to raise funds for the lifesaving treatment and research programs at UM’s Sylvester Comprehensive Cancer Center.
A new Miller School study has identified a cellular pathway used to deactivate innate immune system signaling – a key discovery that could potentially lead to the development of novel vaccines or clinical treatments for chronic inflammatory diseases such as systemic lupus erythematosus and rheumatoid arthritis.
Two veteran Chief Financial Officers have joined the Miller School-UHealth team, bringing a wealth of experience and expertise in healthcare finance to the University of Miami Medical Group and the Hospital Division at a critical time, the new era of healthcare ushered in by the Affordable Care Act.
As the nation marks Breast Cancer Awareness Month, the Sylvester Comprehensive Cancer Center has been awarded a grant by the Flight Attendant Medical Research Institute, Inc. (FAMRI), to further its breast cancer research efforts. The grant of $150,000 is to support and encourage novel, early stage research into breast cancer, a disease associated with exposure to secondhand tobacco smoke.
Many of the University of Miami’s faculty and staff members give generously to the U. This week we profile Bradley Matthews, a sales account executive in UM’s Department of Athletics, who is grateful for the care his young son has received at Bascom Palmer Eye Institute for a rare form of eye cancer.
Led by the Miller School’s Steven E. Lipshultz, M.D., the American Heart Association has issued a major and unprecedented scientific statement on the life-threatening or quality-of-life reducing cardiovascular problems that the growing number of childhood cancer survivors are destined to face decades after their initial treatment. It was published online in advance of print in Circulation, the official journal of the AHA.
Many of the University of Miami’s faculty and staff members give generously to the U. Starting with today’s issue of e-Update, we will profile some of the dynamic employee donors whose gifts to the institution help support a variety of University-related initiatives. This week we profile Amy Ferguson, Director of Major Gifts at Sylvester Comprehensive Cancer Center.
Erin Kobetz, Ph.D., M.P.H., associate professor of public health sciences and Director of the Jay Weiss Institute for Health Equity at Sylvester Comprehensive Cancer Center, is the 2013 recipient of the prestigious Jessie Trice Hero Award for her unwavering commitment to improving the lives of underserved and minority populations.
Extending Sylvester Comprehensive Cancer Center’s outreach to Peru, a University of Miami and Jackson Memorial Hospital team led by Julio C. Barredo, M.D., Director of Children’s Cancer Programs at Sylvester and the Toppel Family Chair in Pediatric Hematology-Oncology, recently conducted the initial training workshop for specialists who will operate Peru’s first comprehensive pediatric bone marrow transplant referral center.
The Sylvester Comprehensive Cancer Center and UM Division of Interventional Oncology have teamed up to host an unforgettable event, “Drive for Life,” from 9 a.m. to 6 p.m. on Saturday, October 12, and Sunday, October 13, at Palm Beach International Raceway, 17133 Bee Line Highway, in Jupiter.
Joining Broward County officials and University of Miami leadership, U.S. Rep. Debbie Wasserman Schultz (FL-23) last week celebrated the opening of Sylvester Comprehensive Cancer Center at its new Plantation location. UM President Donna E. Shalala noted that Sylvester at Plantation also will give Broward patients convenient access to the Miller School of Medicine's more than 100 current clinical trials.
Over the decades, thousands of basic science studies on the thyroid gland and thyroid hormone have been published, but they lacking a standard design, making it difficult to compare and apply their results to improving the diagnosis and treatment of thyroid diseases. The Miller School’s Antonio C. Bianco led the international task force charged with resolving that problem.
Support the Dolphins Cycling Challenge and Sylvester Comprehensive Cancer Center with your next catering order from Corporate Caterers. Now through October 31, the company will donate 10 percent of University catering orders to the DCC, benefiting Sylvester and its cancer research efforts.
Francisco Vega, M.D., Ph.D., an expert in the diagnosis and investigation of cancers arising from the blood and lymphatic system, has been appointed director of hematopathology in the Department of Pathology. Formerly head of the Lymphoma Section at MD Anderson Cancer Center’s Department of Hematopathology, Vega officially joined the Miller School and Sylvester Comprehensive Cancer Center September 1.
A revolutionary brain cancer vaccine clinical trial once limited to patients with newly diagnosed glioblastoma multiforme is now offered to UHealth patients with a recurrent brain tumor. As in the original study, the patient’s own tumor cells are used to develop the vaccine that is designed to target the immune system, offering hope to those with the most common and aggressive form of brain tumor.
The Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine was given a perfect score from the Quality Oncology Practice Initiative (QOPI) Certification Program of the American Society of Clinical Oncology (ASCO). This program awards a three-year certification for outpatient hematology-oncology practices that meet their highest standards for quality cancer care.
Hoping to uncover critical mechanisms needed to develop effective chemotherapeutic approaches for an aggressive form of lung cancer, Priyamvada Rai, Ph.D., assistant professor of medicine in the Division of Gerontology and Geriatric Medicine, will study a novel gene associated with non-small cell lung carcinoma with a $1.5 million, five-year grant she received from the NIH’s National Cancer Institute.
A new study at the Sylvester Comprehensive Cancer Center shows the potential of personalized medicine to guide therapy in early-stage, invasive breast cancer. The study in the rapidly advancing field of molecular subtyping was led by Stefan Glück, M.D., Ph.D., professor of medicine.
Two Bascom Palmer Eye Institute physicians were honored at the Florida Society of Ophthalmology Annual Meeting this past weekend, with Ninel Z. Gregori, M.D., associate professor of clinical ophthalmology, receiving the Michael R. Redmond, M.D., Outstanding Young Ophthalmologist Leadership Award, and J. William Harbour, M.D., professor of ophthalmology, receiving the Shaler Richardson, M.D., Service to Medicine Award.
The University of Miami will pay half of the $150 registration fee for faculty and staff who sign up to ride in the fourth annual Dolphins Cycling Challenge as part of Team UM Sylvester.
A groundbreaking laboratory study indicates that blocking the formation of a cancer-causing protein complex in blood cells could treat a deadly type of leukemia in children and adults. "By shedding new light on the protein-to-protein interactions that lead to acute myeloid leukemia (AML), our study points to a potential therapeutic strategy," said Stephen D. Nimer, M.D., Director of the Sylvester Comprehensive Cancer Center.
Representatives from Hyundai Motor America and South Florida Hyundai dealers gathered at Sylvester Comprehensive Cancer Center on Tuesday morning to award Yolanda Cosme, M.D., hematology/oncology fellow, a $75,000 Hyundai Scholar Grant for her work in pediatric cancer research.
The preferred treatment of many high-risk or relapsed hematologic malignancies remains an allogeneic stem cell transplant. However, patients and physicians often face graft-versus-host disease (GVHD), a frequent and life-threatening complication. Miller School and Sylvester Comprehensive Cancer Center researchers have developed a method to decrease GVHD, while maintaining the benefits of T-cell virus-specific immunity.
The UHealth nursing staff at the Miller School is one of the most vital components of our healthcare team. The March of Dimes, a longtime supporter of the nursing profession, is asking for nominations of distinguished nurses in Miami-Dade or Monroe counties who deserve to be recognized as Nurse of the Year. Please take a moment to nominate a nurse or nursing student who has impacted lives by providing exceptional patient care.
The quarterly Sylvester Board of Governors meeting held Wednesday, June 5, featured a special guest, State Senator Anitere Flores. The lawmaker was recognized for her critical leadership and support during the recent legislative session in Tallahassee, where $10.3 million in appropriations in the state budget was allocated to the Sylvester Comprehensive Cancer Center.
Ronald Desrosiers, Ph.D., a virologist whose seminal discoveries at Harvard Medical School fueled scientific hopes of developing a vaccine for HIV/AIDS, has joined the Miller School’s Department of Pathology, where he will serve as Director of Research Faculty Development and continue his basic science research into viruses that cause AIDS and cancer.
Longtime South Floridian Pat Santangelo is accustomed to speaking in front of crowds, as spokesman for many years with the Florida Highway Patrol and now in Public Affairs for Miami Mayor Tomás Regalado. On Tuesday, May 21, he enlisted the help of his boss and used another method to say thank you to Pasquale Benedetto, M.D., the Sylvester Comprehensive Cancer Center physician who helped him beat a rare cancer.
Essential to jerk seasoning, allspice is known for flavoring Jamaican and other cuisines around the world with a blend of cinnamon, cloves, nutmeg and pepper but, according to a new study by Miller School researchers, the aromatic spice could be known one day for impeding the growth of, or maybe even preventing, prostate cancer, the No. 2 cancer-killer of men in the U.S.
Motivated by its more than 21,000 volunteers, The Pap Corps: Champions for Cancer Research presented its annual gift – this time a check for $3.6 million – to the Sylvester Comprehensive Cancer Center at the Miller School of Medicine. Presented at The Pap Corps May 9 President’s Meeting at the Boca West Country Club in Boca Raton, the check is part of the group’s $25 million commitment to Momentum2.
Decked out in party dresses and tuxedos, nine patients from alex’s place, the pediatric oncology clinic, arrived at Sylvester Comprehensive Cancer Center with fun on their minds on Friday, May 10. They gathered there for a limo ride to the Ritz-Carlton, Fort Lauderdale, to experience “A Prom to Remember.”
The celebration of National Nurses Week at UHealth’s three hospitals reached a crescendo May 10, when Miami-Dade County Mayor Carlos Gimenez presented a proclamation with Miami-Dade Commissioner Javier Souto to “honor the folks that really make hospitals run." Drawing laughter at the festive ceremony at Sylvester Comprehensive Cancer Center, Gimenez said, “I know doctors think they do, but we really know the truth."
Dipen J. Parekh, M.D., professor and Chair of Urology and the Dr. Victor Politano Endowed Chair in Clinical Urology, is the 2013 recipient of the American Urological Association’s prestigious Gold Cystoscope Award. Presented at the association’s annual meeting in San Diego May 8, the award recognizes urologists who have made outstanding contributions to the profession within 13 years of completing their residency training.
For the sixth year in a row, a University of Miami Miller School of Medicine faculty member has been inducted into the prestigious Association of American Physicians, whose members include Nobel laureates and world-renowned researchers and clinicians. This year’s Miller School honoree is Stephen D. Nimer, M.D., Director of the Sylvester Comprehensive Cancer Center, and a visionary physician and scientist.
Long known for his courage on the baseball field, Andre Dawson recently faced an even bigger personal challenge. "When I found out I had prostate cancer, I was scared to death," said Dawson, 58, who was elected to the Hall of Fame after a stellar 21-year career. "But I tackled my cancer head on, and did what was necessary to get better. Now, I hope that sharing my story can save others' lives."
An international team of researchers, including three from the Miller School, has discovered new regions of the human genome that influence obesity in people of African ancestry, as well as others. Contributing to the study from the Miller School were Jennifer J. Hu, Ph.D., Evadnie Rampersaud, Ph.D., and Jorge L. Rodriguez Gil, B.S.
UHealth will present the second in a series of musical performances by students from the Frost School of Music on Wednesday, April 24, at Sylvester Comprehensive Cancer Center. Freshman guitarist Jonah Udall from Rochester, New York, and upright bassist Daniel Montgomery, a sophomore from Berkeley, California, will perform in the Sylvester courtyard from 12:30 to 1 p.m., relocating to the second-floor lobby from 1 to 1:30 p.m.
When Thomas Jambeck was diagnosed with brain tumors caused by metastatic melanoma in 2011, the 64-year-old West Palm Beach resident underwent radiation and two surgeries. One tumor responded, but the second doubled in size. That’s when his physicians sent him to the Miller School for what would be a life-changing procedure.
Two Miller School researchers are part of an international consortium that identified four genetic “spelling mistakes” that can increase the risk of one of the most aggressive forms of breast cancer all too common in South Florida. The findings are reported in one of five studies produced by the Collaborative Oncological Gene-environment Study and published in a special issue of Nature Genetics.
Sylvester Comprehensive Cancer Center/University of Miami Hospital and Clinics has expanded its radiation oncology services.
A new approach for monitoring metastatic breast cancer has "remarkable potential," according to Marc Lippman, M.D., the Kathleen and Stanley Glaser Professor of Medicine and Deputy Director of the University of Miami Sylvester Comprehensive Cancer Center.
Visitors walk through the “Giant Inflatable Colon” stationed in the courtyard of the Sylvester Comprehensive Cancer Center on March 22 as part of a nationwide tour to renowned cancer centers during March, National Colorectal Cancer Awareness Month.
James E. Hoffman, M.D., a specialist in plasma cell diseases, including multiple myeloma and amyloidosis, has joined the Miller School faculty and will provide multidisciplinary cancer specialty care at Sylvester Comprehensive Cancer Center and Sylvester at Deerfield Beach.
The Miami Clinical and Translational Science Institute (CTSI) has awarded funding to two junior investigators at the Miller School through the Mentored Translational Research Scholars Program (K12), and is now accepting applications for the next round of K12 grants.
Florida Governor Rick Scott took a whirlwind tour of the Sylvester Comprehensive Cancer Center while in Miami last week, stopping to shake hands with many surprised patients and employees before meeting with center Director Stephen D. Nimer, M.D., UM President Donna E. Shalala and Miller School Dean Pascal J. Goldschmidt, M.D., to stress his commitment to improving cancer care in the state.
With the extraordinary generosity of David M. Frankel, M.D., and his family, the Miller School’s Department of Dermatology and Cutaneous Surgery has established The Frankel Family Division of Melanocytic Tumors, bringing researchers and physicians one step closer to conquering a formidable foe.
Nurses at UHealth’s Sylvester Comprehensive Cancer Center at Deerfield Beach celebrated Feel the Hugs Day this Valentine's Day to help promote a positive environment for patients and families.
The Miami Clinical and Translational Science Institute (CTSI) will hold its first major University-wide initiative, “CaneSearch,” on Wednesday, February 27, to help identify these goals through a poster session on topics related to obesity, including research, educational, clinical and community-based activities across disciplines.
More than 200 biochemists and molecular biologists from around the world, many of them luminaries in the growing field of metabolism and nutrition research, are gathered in Miami this week for the 46th annual Miami Winter Symposium to explore the interaction of nutrition, genetics, epigenetics and human health.
The St. Baldrick’s Foundation, a volunteer-driven and donor-centered charity dedicated to raising money for childhood cancer research, is proud to award a one-year infrastructure grant of $50,000 to the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine.
In a match “truly made in heaven,” the Jay Weiss Center for Social Medicine and Health Equity is now affiliated with Sylvester Comprehensive Cancer Center, a merger celebrated January 31 at an informal ceremony attended by family members and admirers of two humanitarian giants who championed quality health care for the underserved.
The Karen Mullen Breast Cancer Foundation has awarded $35,000 to Sylvester Comprehensive Cancer Center at the Miller School to support the groundbreaking work of Stefan Glück, M.D., Ph.D., Sylvester Professor of Medicine. The grant specifically supports Glück’s research into estrogen receptors in breast cancer.
Smoking not only causes bladder cancer, it also affects its course, in that people who smoke more have greater likelihood of developing more aggressive and deadly disease. That is one of the conclusions of a study published January 14 in CANCER, a peer-reviewed journal of the American Cancer Society.
Michigan entrepreneur Wayne Lobdell is convinced that the mind-and-body wellness techniques his UHealth doctors introduced him to in South Florida are key to his recovered good health – so convinced that he and his wife Terry are ensuring all patients who visit UHealth’s Sylvester Comprehensive Cancer Center at Deerfield Beach can access a broad range of holistic mind-body preventive and therapeutic interventions.
The Saul and Theresa Esman Foundation has made a pledge of $450,000 to support UHealth’s Sylvester Comprehensive Cancer Center at the Miller School.