Sylvester Comprehensive Cancer Center

Lorraine Portelance, M.D.

Lorraine Portelance, M.D.

Associate Professor of Radiation Oncology

Description of Research

The main focus of Dr. Portelance's research has been the use of Intensity Modulated Radiation Therapy (IMRT) for the treatment of patients with gynecological and gastro-intestinal malignancies and the use of image guided high dose rate brachytherapy for patients with gynecological cancer. A second field of interest for his research has been on the development of medical education tools.

She has been involved with collaborative group clinical trials, serving as a co-principal investigator for a Radiation Therapy Oncology Group (RTOG) clinical trial (RTOG 0418). Dr. Portelance is also an active member of the international gynecological cancer study group (IGCSG), the NIH cervix task force, RTOG gynecological cancer tumor site steering committee and advanced technology integration committee.

She joined the radiation oncology team at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine in September 2010. She is committed to contribute to the development of clinical research for patients with gastro-intestinal and gynecological cancer. As well, she acts as the RTOG PI for our institution since January 2011 and she is determined to develop the department’s involvement with the RTOG and strengthen Sylvester’s position as a key player of this organization.

Highlights

Selected Cancer-Related Publications

  • Klopp AH, Moughan J, Portelance L, Miller BE, Salehpour MR, Hildebrandt E, Nuanjing J, D'Souza D, Souhami L, Small W Jr, Gaur R, Jhingran A. Hematologic toxicity in RTOG 0418: a phase 2 study of postoperative IMRT for gynecologic cancer. Int J Radiat Oncol Biol Phys 86:83-90,2013 Read more »
  • Gay HA, Barthold HJ, O'Meara E, Bosch WR, El Naqa I, Al-Lozi R, Rosenthal SA, Lawton C, Lee WR, Sandler H, Zietman A, Myerson R, Dawson LA, Willett C, Kachnic LA, Jhingran A, Portelance L, Ryu J, Small W Jr, Gaffney D, Viswanathan AN, Michalski JM. Pelvic normal tissue contouring guidelines for radiation therapy: a radiation therapy oncology group consensus panel atlas. Int J Radiat Oncol Biol Phys 83:e353-62,2012 Read more »
  • Hosein PJ, Macintyre J, Kawamura C, Maldonado JC, Ernani V, Loaiza-Bonilla A, Narayanan G, Ribeiro A, Portelance L, Merchan JR, Levi JU, Rocha-Lima CM. A retrospective study of neoadjuvant FOLFIRINOX in unresectable or borderline-resectable locally advanced pancreatic adenocarcinoma. BMC Cancer 12:199,2012 Read more »
  • Jhingran A, Winter K, Portelance L, Miller B, Salehpour M, Gaur R, Souhami L, Small W Jr, Berk L, Gaffney D. A phase II study of intensity modulated radiation therapy to the pelvis for postoperative patients with endometrial carcinoma: radiation therapy oncology group trial 0418. Int J Radiat Oncol Biol Phys 84:e23-8,2012 Read more »

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