Pearl Seo, M.D.
Assistant Professor of Medicine
Description of Research
Dr. Seo’s previous research endeavors included the understanding of the performance status trajectory in the older person with cancer through the evaluation of the interplay of co-morbid illness with cancer treatment. She aimed to identify potential areas of weakness and strength in the older cancer patient and cancer survivors for further description, measurement, and interventions for improvement. Dr. Seo’s research also has included studies in breast cancer prevention in high-risk older post-menopausal women; aiming to develop a model for risk assessment in this cohort. Her current work on a biomarker project focuses on obtaining gene methylation status from circulating plasma DNA in women with in-situ breast disease and breast cancer. Dr. Seo is interested in investigating if patterns of DNA methylation in the blood of women with breast cancer are similar to the DNA methylation pattern found in their breast cancer, and if blood methylation is predictive of the type and stage of breast cancer diagnosed.
Selected Cancer-Related Publications
- Iorns E, Hnatyszyn HJ, Seo P, Clarke J, Ward T, Lippman M. The Role of SATB1 in Breast Cancer Pathogenesis. J Natl Cancer Inst 102:1284-96, 2010 Read more »