Clinical Trials

Translating research breakthroughs into more effective treatments remains one of Sylvester’s highest priorities. Sylvester conducts more clinical research than any other institution in South Florida and has a wide range of trials, with 168 currently underway.

Search for cancer trials on the UHealth Clinical Trials website »

For more information, view our Clinical Trials FAQs or call the Sylvester Information Center at 305-243-1000 or 800-545-2292.

Phase I Clinical Trials Program

The National Institutes of Health Roadmap for Medical Research calls for providing “the necessary foundation for advancing basic and clinical research” to speed promising therapies from the laboratory into the clinic for patient care. The Phase I Clinical Trials Program at Sylvester was created to fulfill this philosophy within a safe environment to provide patient care.

The program is comprised of a multidisciplinary team of physicians, scientists, pharmacists, laboratory technicians, nurses, statisticians, research coordinators, and data managers. This team has dedicated laboratory, pharmacy, and chemotherapy administration areas, which all work together to provide the highest standard of care to patients who participate in Phase I trials.

Phase I trials are the first studies in humans, and, as a result, an important step to transition novel treatments from the bench to the bedside. The Phase I Clinical Trials Program helps physicians and scientists establish collaborative relationships that often translate into more treatment choices for patients.

The Phase I Clinical Trials Program at Sylvester is South Florida’s only academic Phase I testing center dedicated to drug development for cancer patients.

Data Safety & Monitoring Plan

Sylvester functions as a matrix cancer center within the University of Miami Miller School of Medicine. All clinical trials conducted at Sylvester must include provisions for data and safety monitoring. The extent of monitoring may vary based on the degree of risk, the sponsor, and the size and complexity of the trial.

The cancer center has developed the Data Safety and Monitoring Plan to ensure data and safety monitoring, as well as protocol compliance, for all institutional clinical trials involving therapeutic or preventive interventions. An institutional clinical trial is defined for purposes of this plan as a clinical trial initiated and conducted by a member of the University of Miami faculty or staff, not subject to monitoring by an outside agency (e.g. industry, cooperative group, NCI, NIH, other institution).